Dnmt3L Products

Antibodies
Dnmt3L Antibody
Dnmt3L Antibody
NBP2-27098
Species: Hu, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
Dnmt3L Antibody
Dnmt3L Antibody
NBP2-27099
Species: Hu, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
Dnmt3L Antibody
Dnmt3L Antibody
H00029947-D01P
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Antibody Pairs
Dnmt3L Antibody Pair
Dnmt3L Antibody Pair
H00029947-AP21
Species: Hu
Applications: S-ELISA
Lysates
Dnmt3L Overexpression Lysate ...
Dnmt3L Overexpression Lysate (Native)
NBL1-09972
Applications: WB
Dnmt3L Overexpression Lysate ...
Dnmt3L Overexpression Lysate (Native)
NBL1-09971
Applications: WB
Dnmt3L Overexpression Lysate ...
Dnmt3L Overexpression Lysate (Dena...
H00029947-T01
Species: Hu
Applications: WB
Proteins
Dnmt3L Recombinant Protein An ...
Dnmt3L Recombinant Protein Antigen
NBP2-39076PEP
Species: Hu
Applications: AC
Dnmt3L Recombinant Protein
Dnmt3L Recombinant Protein
NBP2-51647
Species: Hu
Applications: PAGE
Dnmt3L Recombinant Protein
Dnmt3L Recombinant Protein
NBP2-51708
Species: Hu
Applications: PAGE
RNAi
Dnmt3L RNAi
Dnmt3L RNAi
H00029947-R02
Species: Hu
Applications: RNAi, RNAi SP
Dnmt3L RNAi
Dnmt3L RNAi
H00029947-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

DNMT 3L is a nuclear protein which has similarity to DNA methyltransferases, involved in de novo methylation of CpG islands. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 29947
Alternate Names
  • DNA (cytosine-5)-methyltransferase 3-like
  • human cytosine-5-methyltransferase 3-like protein, 10cytosine-5-methyltransferase 3-like protein
  • MGC1090
  • DNA (cytosine-5-)-methyltransferase 3-like

Research Areas for Dnmt3L

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research

PTMs for Dnmt3L

Learn more about PTMs related to Dnmt3L.

Methylation
Demethylation
Acetylation
Phosphorylation

Bioinformatics Tool for Dnmt3L

Discover related pathways, diseases and genes to Dnmt3L. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Dnmt3L Blog Posts

Check out the latest blog posts on Dnmt3L.
The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies
Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...    Read more.
The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...    Read more.
Read more Dnmt3L related blogs.