DNAI1 Antibody (JM11-38)

Immunohistochemistry-Paraffin: DNAI1 Antibody (JM11-38) [NBP2-66804] - Analysis of paraffin-embedded mouse testes tissue using anti-Dynein intermediate chain 1 antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: DNAI1 Antibody (JM11-38) [NBP2-66804] - Analysis of paraffin-embedded mouse fallopian tube tissue using anti-Dynein intermediate chain 1 antibody. Counter stained with hematoxylin.

Product Discontinued

DNAI1 Antibody (JM11-38) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Recombinant protein within Human DNAI1 aa 1-240 / 699. (SwissProt: Q9UI46 Human; SwissProt: Q8C0M8 Mouse; SwissProt: Q5XIL8 Rat)
• Localization: Cell projection, Cilium, Cytoplasm, Cytoskeleton, Dynein, Microtubule.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: DNAI1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for DNAI1 Antibody (JM11-38)

• Axonemal dynein intermediate chain 1
• CILD1MGC26204
• dynein intermediate chain DNAI1
• dynein, axonemal, intermediate chain 1
• dynein, axonemal, intermediate polypeptide 1
• ICS
• ICS1
• immotile cilia syndrome 1
• PCDdynein intermediate chain 1, axonemal

Background

The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generatingproteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the baseof the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodesan intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result inabnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.(provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DNAI1