DMRT3 Antibody

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Immunohistochemistry-Paraffin: DMRT3 Antibody [NBP2-69049] - Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

DMRT3 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: MNGYGSPYLYMGGPVSQPPRAPLQRTPKC
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DMRT3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6
Control Peptide
DMRT3 Recombinant Protein Antigen (NBP2-69049PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for DMRT3 Antibody

  • DMRTA3
  • DMRT-like family A3
  • doublesex and mab-3 related transcription factor 3
  • doublesex- and mab-3-related transcription factor 3
  • MGC142144
  • testis-specific protein

Background

DMRT3, also known as Doublesex and mab-3-related transcription factor 3, is a 51.2 kDa, 472 amino acid protein that is involved in arranging spinal circuits, developing neuronal specification in particular spinal cord neurons, and regulating transcription during sexual development. Diseases and disorders such as gonadoblastoma, Turner syndrome, sex reversal, Rokitansky-Kuster-Hauser syndrome, and squamous cell carcinoma have been studied with the protein. The protein interacts in transcription pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DMRT3