DMRT2 Antibody (PCRP-DMRT2-1B11)

Flow Cytometry: DMRT2 Antibody (PCRP-DMRT2-1B11) [NBP3-13840] - Flow Cytometric Analysis of PFA-fixed HeLacells. DMRT2 antibody (PCRP-DMRT2-1B11) followed bygoat anti-mouse IgG-CF488 (blue); isotypecontrol (red).

Protein Array: DMRT2 Antibody (PCRP-DMRT2-1B11) [NBP3-13840] - Analysis of Protein Array containing more than 19,000 full-length human proteins using DMRT2 Antibody (PCRP-DMRT2-1B11).

• Reactivity: Hu
• Applications: WB, Flow, MA
• Clone: PCRP-DMRT2-1B11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

DMRT2 Antibody (PCRP-DMRT2-1B11) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14270)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
• Immunogen: Recombinant full-length human DMRT2 protein (Uniprot: Q9Y5R5)
• Localization: Nucleus
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DMRT2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-2 ug/million cells
  • Protein Array
  • Western Blot 1-2 ug/ml
• Theoretical MW: 62 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for DMRT2 Antibody (PCRP-DMRT2-1B11)

• doublesex and mab-3 related transcription factor 2
• doublesex- and mab-3-related transcription factor 2
• Doublesex-like 2 protein
• DSXL2
• DSXL-2
• terra-like protein

Background

DMRT2, also known as Doublesex and mab-3-related transcription factor 2, consists of a 61.8 kDa, a 24.5 kDa, and a 36.9 kDa isoform and is involved in regulating activation of the gene MYF5 as a transcription factor during embryogenesis and somite development. Current research has linked the protein to diseases such as sex reversal, attention deficit hyperactivity disorder, leukemia, anemia, and gonadal dysgenesis. The protein interacts with UBC, CCDC18, BCLAF1, RPS3, and MYBBP1A in transcription pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DMRT2
• Uniprot:
  • Q9Y5R5(Human)