DMRT1 Antibody (SR1561) - BSA Free

Western Blot: DMRT1 Antibody (SR1561) [NBP3-21894] - Western blot analysis using NBP3-21894 in HL-60 cell lysate.

• Reactivity: Hu
• Applications: WB, IP
• Clone: SR1561
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

DMRT1 Antibody (SR1561) - BSA Free Summary

• Description: Novus Biologicals Rabbit DMRT1 Antibody (SR1561) - BSA Free (NBP3-21894) is a recombinant monoclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human DMRT1 (Uniprot #: Q9Y5R6)
• Specificity: Detects endogenous levels of total DMRT1
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: DMRT1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:80
  • Western Blot 1:500-1:2000
• Theoretical MW: 34 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for DMRT1 Antibody (SR1561) - BSA Free

• DM domain expressed in testis 1
• DMT1DM domain expressed in testis protein 1
• doublesex and mab-3 related transcription factor 1
• doublesex- and mab-3-related transcription factor 1

Background

DMRT1 is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DMRT1