DLST Antibody (4D7) - Azide and BSA Free

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug] - Detection against Immunogen (36.63 KDa) .

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug] - Analysis of DLST expression in transfected 293T cell line by DLST monoclonal antibody (M01), clone 4D7. Lane 1: DLST transfected lysate (Predicted MW: 48.8 KDa). Lane 2: Non-transfected lysate.

Western Blot: DLST Antibody (4D7) [H00001743-M01-100ug] - Analysis of DLST expression in PC-12.

ELISA: DLST Antibody (4D7) [H00001743-M01-100ug] - Detection limit for recombinant GST tagged DLST is 0.3 ng/ml as a capture antibody.

• Reactivity: Hu, Rt
• Applications: WB, ELISA
• Clone: 4D7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

DLST Antibody (4D7) - Azide and BSA Free Summary

• Immunogen: DLST (NP_001924, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFFRTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAE
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: DLST
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DLST Antibody (4D7) - Azide and BSA Free

• 2-oxoglutarate dehydrogenase complex component E2
• dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutaratecomplex)
• Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenasecomplex
• dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutaratedehydrogenase complex, mitochondrial
• DLTS
• E2K
• EC 2.3.1
• EC 2.3.1.61
• OGDC-E2

Background

DLST, also known as Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, is a 48.8 kDa, 453 amino acid protein that is involved in catalyzing the reaction of 2-oxoglutarate into succinyl-CoA and carbon dioxide. Current research is investigating the effect of the protein on malaria, neurodegeneration, pneumonia, cat-scratch disease, ataxia, prostatitis, Parkinson's disease, and Alzheimer's disease. The protein is involved in lysine degradation, citric acid cycle (TCA cycle), and metabolism pathways where it interacts with FLII, ATP6V1B2, HSPD1, UMPS, and DDOST.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DLST
• Entrez:
  • 1743(Human)
• OMIM:
  • 126063(Human)
• Uniprot:
  • NP_001924(Human)