delta 2 Catenin Antibody (6E11)

Western Blot: delta 2 Catenin Antibody (6E11) [H00001501-M01] - CTNND2 monoclonal antibody (M01), clone 6E11. Analysis of CTNND2 expression in K-562.

Western Blot: delta 2 Catenin Antibody (6E11) [H00001501-M01] - CTNND2 monoclonal antibody (M01), clone 6E11 Analysis of CTNND2 expression in PC-12.

Western Blot: delta 2 Catenin Antibody (6E11) [H00001501-M01] - CTNND2 monoclonal antibody (M01), clone 6E11. Analysis of CTNND2 expression in Raw 264.7.

ELISA: delta 2 Catenin Antibody (6E11) [H00001501-M01] - delta 2 Catenin Antibody (6E11) [H00001501-M01] - Detection limit for recombinant GST tagged CTNND2 is 0.03 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: 6E11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

delta 2 Catenin Antibody (6E11) Summary

• Immunogen: CTNND2 (NP_001323, 1081 a.a. ~ 1190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYRNSYGAPAEDIKHNQVSAQPVPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASEYTMHLG
• Specificity: CTNND2 - catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CTNND2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Western Blot 1:500
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for delta 2 Catenin Antibody (6E11)

• catenin (cadherin-associated protein), delta 2 (neural plakophilin-relatedarm-repeat protein)
• catenin delta-2
• Delta-catenin
• GT24T-cell delta-catenin
• Neural plakophilin-related ARM-repeat protein
• Neurojungin
• NPRAPneurojungin

Background

Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids long. These proteins can be divided into subfamilies based on the number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1 (MIM 601045), CTNND2, PKP1 (MIM 601975), PKP2 (MIM 602861), PKP4 (MIM 604276), and ARVCF (MIM 602269), have 10 armadillo repeats each (Bonne et al., 1998 [PubMed 9721216]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for delta 2 Catenin Antibody (H00001501-M01)(2)

Publications using H00001501-M01

• Koutras C, Levesque G. Identification of Novel NPRAP/delta-Catenin-Interacting Proteins and the Direct Association of NPRAP with Dynamin 2. PLoS One. 2011-10-14 [PMID: 22022388]
• Halbert D, Domenyuk V, Spetzler D et al. Aptamers and uses thereof United States Patent Application US 9958448 B2 2018-01-01

Bioinformatics

• Gene Symbol: CTNND2
• Entrez:
  • 1501(Human)
• OMIM:
  • 123450(Human)
• Uniprot:
  • NP_001323(Human)