DAB2 Antibody [Allophycocyanin]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Allophycocyanin

DAB2 Antibody [Allophycocyanin] Summary

• Immunogen: E. coli-derived recombinant human DAB2
  Lys630-Ala770
  Accession # P98082
• Specificity: Detects human DAB2 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: DAB2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for DAB2 Antibody [Allophycocyanin]

• DAB2
• Differentially-expressed protein 2
• disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
• disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
• Disabled-2
• DOC2
• DOC-2DOC2disabled homolog 2
• FLJ26626
• mitogen-responsive phosphoprotein

Background

Disabled-2 (Dab2) is a component of the CSF-1 signal transduction pathway. Dab2 is involved in the regulation of cytoskeleton based functions by regulating cell positioning, inducing marcrophage adhesion, or regulation of protein trafficking of endocytosis involved proteins (1,2). Dab2 has been implicated in regulating the homeostasis of epithelial differentiation, where Dab2 is involved in endodermal cell formation, differentiation, and organization. Dab2 mRNA expression is common in normal ovarian epithelia cells but low or lack of expression is seen in ovarian carcinoma cell lines (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DAB2