Cytokeratin 10 Antibody (KRT10/844) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
KRT10/844
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 532

Order Details

Cytokeratin 10 Antibody (KRT10/844) [Alexa Fluor® 532] Summary

Immunogen
Recombinant human KRT10 protein
Localization
Cytoplasmic
Marker
Suprabasal Epithelial Marker
Specificity
This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KRT10
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cytokeratin 10 Antibody (KRT10/844) [Alexa Fluor® 532]

  • BCIE
  • BIE
  • CK10
  • CK-10
  • cytokeratin 10
  • Cytokeratin-10
  • EHK
  • K10keratosis palmaris et plantaris
  • Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)
  • keratin 10
  • keratin, type I cytoskeletal 10
  • keratin-10
  • KPP

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47825AF350
Alexa Fluor 405 NBP2-47825AF405
Alexa Fluor 488 NBP2-47825AF488
Alexa Fluor 532 NBP2-47825AF532
Alexa Fluor 594 NBP2-47825AF594
Alexa Fluor 647 NBP2-47825AF647
Alexa Fluor 700 NBP2-47825AF700
Alexa Fluor 750 NBP2-47825AF750
Allophycocyanin NBP2-47825APC
Allophycocyanin/Cy7 NBP2-47825APCCY7
Biotin NBP2-47825B
DyLight 350 NBP2-47825UV
DyLight 405 NBP2-47825V
DyLight 488 NBP2-47825G
DyLight 550 NBP2-47825R
DyLight 594 NBP2-47825DL594
DyLight 650 NBP2-47825C
DyLight 680 NBP2-47825FR
DyLight 755 NBP2-47825IR
FITC NBP2-47825F
HRP NBP2-47825H
Janelia Fluor 549 NBP2-47825JF549
Janelia Fluor 646 NBP2-47825JF646
PE NBP2-47825PE
PE/Atto594 NBP2-47825PEATT594
PE/Cy5.5 NBP2-47825PECY55
PE/Cy7 NBP2-47825PECY7
PerCP NBP2-47825PCP

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Bioinformatics

Gene Symbol KRT10