Cytochrome P450 4F11 Antibody (F21 P6 F5) - BSA Free

Immunohistochemistry: Cytochrome P450 4F11 Antibody (F21 P6 F5) [NBP2-66614] - A. Immunohistochemical staining of human liposarcoma cells using CYP4F11 antibody (Cat. No. NBP2-66614).B. Western blot using CYP4F11 antibody one normal (2) and cancerous (3) kidney cell lysates.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clone: F21 P6 F5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Cytochrome P450 4F11 Antibody (F21 P6 F5) - BSA Free Summary

• Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human Cytochrome P450 4F11 protein (Uniprot: A8K059) and mouse myeloma Ag8563 cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CYP4F11
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1-5 ug/ml
  • Immunohistochemistry-Paraffin 1-5 ug/ml
  • Western Blot 1-2 ug/ml
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.08% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for Cytochrome P450 4F11 Antibody (F21 P6 F5) - BSA Free

• CYPIVF11
• cytochrome P450 4F11
• cytochrome P450, family 4, subfamily F, polypeptide 11
• cytochrome P450, subfamily IVF, polypeptide 11
• EC 1.14.14.1

Background

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYP4F11
• Uniprot:
  • A8K059(Human)