Cytochrome P450 1A1 Antibody

Images

 
Western Blot: Cytochrome P450 1A1 Antibody [NBP1-97762] - NBP1-97762 (0.1ug/ml) staining of Rat Lung lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Concentration
0.5 mg/ml

Order Details

Cytochrome P450 1A1 Antibody Summary

Immunogen
Peptide with sequence C-QDRKLDENANVQLSD corresponding to internal region according to Uniprot Mouse NP_001129531.1.
Specificity
This antibody is not expected to cross-react with the similar P450 1A2
Clonality
Polyclonal
Host
Goat
Gene
CYP1A1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Conjugate
Unconjugated
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Approx. 55 kDa band observed in rat lung lysates (calculated MW of 59.2 kDa band according to mouse NP_001129531.1 and 59.4 kDa band according to rat NP_036672.).
Publications
Read Publication using NBP1-97762.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse.

Alternate Names for Cytochrome P450 1A1 Antibody

  • AHH
  • AHRR
  • aryl hydrocarbon hydroxylase
  • CP11
  • CYP1
  • CYPIA1
  • cytochrome P1-450, dioxin-inducible
  • cytochrome P450 1A1
  • Cytochrome P450 form 6
  • cytochrome P450, family 1, subfamily A, polypeptide 1
  • Cytochrome P450-C
  • Cytochrome P450-P1
  • EC 1.14.14.1
  • flavoprotein-linked monooxygenase
  • P1-450
  • P450-C
  • P450DX
  • subfamily I (aromatic compound-inducible), polypeptide 1
  • xenobiotic monooxygenase

Background

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cytochrome P450 1A1 Antibody (NBP1-97762)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol CYP1A1
Entrez
Uniprot

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