Cystatin E/M/CST6 Antibody Pair [HRP] Summary
| Description |
Solid Phase sandwich ELISA for the quantitative determination of Human Cystatin E/M/CST6. |
| Specificity |
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human Cystatin E/M/CST6. |
| Standard Curve Range |
7.81-500 pg/ml (example only; lot dependent) |
| Sensitivity |
7.8 pg/ml (example only; lot dependent) |
| Assay Type |
Sandwich ELISA |
| Sample Volume |
100 ul |
| Gene |
CST6 |
Applications/Dilutions
Packaging, Storage & Formulations
| Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
|
Components
|
- Mouse Monoclonal Detection Antibody (HRP-conjugated)
- Standard
|
Alternate Names for Cystatin E/M/CST6 Antibody Pair [HRP]
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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