After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.
HAF017). A specific band was detected for Cystatin E/M at approximately 13 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody." class="big_lightbox" target="_blank">
HAF007). A specific band was detected for Cystatin E/M at approximately 13 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
![Western Blot Cystatin E/M/CST6 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Cystatin_E_M_AF1286_Western_Blot_20495.jpg)
![Western Blot Cystatin E/M/CST6 Antibody (211515) [Unconjugated]](http://images.novusbio.com/images/antibody/Cystatin_E_M_MAB1286_Western_Blot_20502.jpg)
![Sandwich ELISA Cystatin E/M/CST6 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Cystatin-E-M-CST6-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79464-img0001.jpg)
![Simple Western Cystatin E/M/CST6 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Cystatin_E_M_AF1286_Simple_Western_20496.jpg)
![Western Blot Cystatin E/M/CST6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1286_human-cystatin-e-m-affinity-purified-polyclonal-ab-812025548570.jpg)
![Western Blot Cystatin E/M/CST6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1286_human-cystatin-e-m-affinity-purified-polyclonal-ab-8120255552837.jpg)
![Immunohistochemistry Cystatin E/M/CST6 Antibody (211515) [Unconjugated]](http://images.novusbio.com/images/antibody/Cystatin_E_M_MAB1286_Immunohistochemistry_6944.jpg)
