CYP24A1 Antibody

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Western Blot: CYP24A1 Antibody [NBP1-52111] - Analysis of CYP24A1 in Human Liver lysate (35ug protein in RIPA buffer) using NBP1-52111 at 0.1 ug/m. Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

CYP24A1 Antibody Summary

Immunogen
Peptide with sequence C-RKYDIQATDN corresponding to internal region according to NP_000773.2, NP_001122387.1.
Epitope
C-RKYDIQATDN
Specificity
This antibody is expected to recognize both reported isoforms (NP_000773.2; NP_001122387.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CYP24A1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 50 kDa band observed in human and rat liver lysates (calculated MW of 51.2 kDa band according to NP_001122387.1).
Publications
Read Publication using NBP1-52111.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CYP24A1 Antibody

  • 25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
  • CP241
  • CYP241,25-alphadihydroxyvitamin D3 24-hydroxylase
  • Cytochrome P450 24A1
  • cytochrome P450, family 24, subfamily A, polypeptide 1,24-OHase
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
  • Cytochrome P450-CC24
  • EC 1.14.13.n4
  • exo-mitochondrial protein
  • MGC126273
  • MGC126274
  • P450-CC24
  • vitamin D 24-hydroxylase
  • Vitamin D(3) 24-hydroxylase

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CYP24A1 Antibody (NBP1-52111)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CYP24A1
Entrez
Uniprot