CTPS2 Antibody - BSA Free

Immunoprecipitation:CTPS2 AntibodyNBP3-30617] -Detection of human CTPS2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) prepared using NETN buffer from 293T cells. Antibodies: Affinity purified rabbit anti-CTPS2 antibody NBP3-30617 (lot NBP3-30617-1) used for IP at 6 µg per reaction. CTPS2 was also immunoprecipitated by rabbit anti-CTPS2 antibody. For blotting immunoprecipitated CTPS2, NBP3-30617 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CTPS2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CTPS2 Antibody - BSA Free (NBP3-30617) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Between 536 and 586
• Assay Type: [Assay Type]
• Sample Volume: [Sample Volume]
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CTPS2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-citrate/phosphate buffer, pH 7 to 8
• Preservative: 0.09% Sodium Azide
• Purity: Affinity purified

Alternate Names for CTPS2 Antibody - BSA Free

• CTP synthase 2
• CTP synthase II
• CTP synthetase 2
• CTP synthetase isoform
• CTP synthetase type 2
• cytidine 5'-triphosphate synthetase 2
• DKFZp686C17207
• EC 6.3.4.2
• FLJ43358
• MGC32997
• UTP--ammonia ligase 2
• UTP-ammonia ligase

Background

The protein encoded by the CTPS2 gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamineto glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play animportant role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA.Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein.Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variantsencoding the same protein have been described for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTPS2