CSTF2T Antibody - Azide and BSA Free

Western Blot: CSTF2T Antibody [H00023283-B01P] - Analysis of CSTF2T expression in rat brain.

Western Blot: CSTF2T Antibody [H00023283-B01P] - Analysis of CSTF2T expression in transfected 293T cell line by CSTF2T polyclonal antibody. Lane 1: CSTF2T transfected lysate(67.76 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CSTF2T Antibody - Azide and BSA Free Summary

• Immunogen: CSTF2T (NP_056050.1, 1 a.a. - 616 a.a.) full-length human protein. MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CSTF2T
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot

Reactivity Notes

This product is reactive against Human,Rat.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CSTF2T Antibody - Azide and BSA Free

• CF-1 64 kDa subunit tau variant
• CF-1 64 kDa subunit tau
• Cleavage stimulation factor 64 kDa subunit tau variant
• cleavage stimulation factor 64 kDa subunit tau
• cleavage stimulation factor subunit 2 tau variant
• cleavage stimulation factor subunit 2 tau
• cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
• CSTF 64 kDa subunit tau variant
• CstF-64T
• DKFZp434C1013
• KIAA0689CSTF 64 kDa subunit tau
• tauCstF-64

Background

CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously; however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CSTF2T
• Uniprot:
  • NP_056050.1(Human)