CRIPTO Antibody (89633) [Allophycocyanin/Cy7]

• Reactivity: Hu, Pm
• Applications: Flow
• Clone: 89633
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin/Cy7

CRIPTO Antibody (89633) [Allophycocyanin/Cy7] Summary

• Immunogen: E. coli-derived recombinant human Cripto-1
  Arg38-Tyr188
  Accession # P13385
• Specificity: Detects human and primate Cripto-1 in ELISAs. In sandwich immunoassays, no cross-reactivity with recombinant mouse Cripto-1, recombinant human (rh) EGF, rhTGF‑ alpha , rhTGF-beta 1, rhTGF-beta 2, rhTGF-beta 3, or rhCryptic is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CRIPTO
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Cy is a registered trademark of Global Life Sciences Solutions Germany GmbH.

Alternate Names for CRIPTO Antibody (89633) [Allophycocyanin/Cy7]

• CFC-2
• CR
• Cripto
• Cripto-1 growth factor
• Cripto-1
• CRIPTOCRGF
• Epidermal growth factor-like cripto protein CR1
• TDGF1
• TDGF-1
• teratocarcinoma-derived growth factor 1

Background

Teratocarcinoma-derived growth factor 1 (TDGF1), also known as CRIPTO, is expressed both in ES cells and during the early phases of embryo development. During development, CRIPTO is thought to play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. In adults, it is reactivated in a wide range of epithelial cancers.

CRIPTO-1 antibodies are useful tools for studying embryonic development and certian cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CRIPTO