Predicted cross-reactivity based on sequence identity: Marmoset (94%). Summary of Expression: CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for CRHR1/CRF1 Antibody
corticotropin releasing hormone receptor 1
corticotropin-releasing factor receptor 1
corticotropin-releasing factor type 1 receptor
Corticotropin-releasing hormone receptor 1
seven transmembrane helix receptor
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for CRHR1/CRF1 Antibody (NLS1778). (Showing 1 - 1 of 1 FAQs).
He wonders whether it is suitable for mouse frozen section by IF. Can you so kind to help him and me?
Our CRF1 antibody with catalogue number NLS1778 has been validated for use with samples from mouse, however it has only currently been tested for immunohistochemistry with paraffin-embedded tissue, and for immunocytochemistry. It has not yet been tested for immunohistochemistry with frozen tissue. Please refer your customer to our Innovator's Reward if they wish to try using this antibody for IHC with their frozen mouse tissue samples.
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Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.