CRACC/SLAMF7 Antibody (235614) [Alexa Fluor® 488]

Images

 
Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon APC‑conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Mouse Anti-Human CRACC/SLAMF7 Alexa Fluor® ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
235614
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 488

CRACC/SLAMF7 Antibody (235614) [Alexa Fluor® 488] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human CRACC/SLAMF7
Lys27-Ser225
Accession # Q9NQ25
Specificity
Detects human CRACC/SLAMF7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human NTB-AR is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SLAMF7
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 5 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CRACC/SLAMF7 Antibody (235614) [Alexa Fluor® 488]

  • 19A
  • CD2 subset 1
  • CD2-like receptor activating cytotoxic cells
  • CD319 antigen
  • CD319
  • CRACC
  • CRACCCD2-like receptor-activating cytotoxic cells
  • CS119A24 protein
  • Membrane protein FOAP-12
  • novel LY9 (lymphocyte antigen 9) like protein
  • Novel Ly9
  • Protein 19A
  • SLAM family member 7
  • SLAMF7

Background

CRACC, also known as CSI (CD2 subset I) and CD319, is a type I transmembrane protein belonging to the CD2 subset of the Ig superfamily. CRACC is expressed on most NK cells and subsets of CD8+ cells, CD4+ cells and B cells. CRACC may play a role in the activation and effector function of T cells and NK cells and likely participates in B cell adhesion. Over amino acids (aa) 27-225, human and mouse SLAMF7 share 53% aa sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLAMF7
Entrez
Uniprot