Human Complement C4 ELISA Kit (Colorimetric)

Product Discontinued

Human Complement C4 ELISA Kit (Colorimetric) Summary

• Description: Quality control test: Standard curve. C4 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human complement C4 in urine saliva and cell culture supernatants.
• Sensitivity: 0.08 ng/mL
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 7.30%
• Intra-Assay: CV% < 4.60%
• Spike Recovery: 98.50%
• Sample Volume: 50 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: C4A

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human Complement C4 ELISA Kit (Colorimetric)

• C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2
• C4
• complement component 4A (Rodgers blood group)
• RG

Background

C4 consists of three polypeptide chains (alpha, molecular weight 95 kDa, beta, molecular weight 75 kDa and gamma, molecular weight 33 kDa) and is usually present in serum at 200-600mg/L. It is a protein of the classical complement pathway. When activated by C1s, a peptide C4a is released and the generated C4b binds C2 which is in turn cleaved by C1s to produce the classical pathway C3 convertase, namely C4b2a. C4b also has opsonin activity and binds to macrophages and neutrophils via their CR1 receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Complement C4 ELISA Kit (KA1021)(3)

Publications using KA1021

• Ramos-Casals M, Brito-Zeron P, Nardi N et al. Successful treatment of severe Raynaud's phenomenon with bosentan in four patients with systemic sclerosis. Rheumatology (Oxford) 2004-11-01 [PMID: 15502001]
• Sacks S, Zhou W. The effect of locally synthesised complement on acute renal allograft rejection. J Mol Med 2003-06-25 [PMID: 12827269]
• Sahu A, Lambris JD. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol Rev 2001-04-01 [PMID: 11414361]

FAQs for Complement C4 ELISA Kit (KA1021). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: C4A