Complement C3b Antibody (2B10B9B2) - BSA Free Summary
Immunogen |
The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. |
Isotype |
IgM |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
C3 |
Purity |
Tissue culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunoassay
- Western Blot 1:100-1:2000
|
Packaging, Storage & Formulations
Storage |
Store at 4C. |
Buffer |
Culture medium |
Preservative |
0.02% Sodium Azide |
Concentration |
This product is unpurified. The exact concentration of antibody is not quantifiable. |
Purity |
Tissue culture supernatant |
Alternate Names for Complement C3b Antibody (2B10B9B2) - BSA Free
Background
The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. The antibody reacts both with intact C3 and C3b. The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha-chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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