COCO/DAND5 Antibody [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: CoraFluor 1

COCO/DAND5 Antibody [CoraFluor™ 1] Summary

• Immunogen: E. coli-derived recombinant human COCO (R&D Systems, Catalog # 3047-CC)
  Arg23-Ala189
  Accession # NP_689867
• Specificity: Detects human COCO in direct ELISAs and Western blots. In these formats, less than 1% cross-reactivity with recombinant mouse COCO is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: DAND5
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for COCO/DAND5 Antibody [CoraFluor™ 1]

• CER2CRL2
• Cerberus 2
• Cerberus like-2
• cerberus-like 2
• Cerberus-like protein 2
• CERL2
• cerl-2
• CKTSF1B3
• CKTSF1B3MGC126849
• COCO
• Cysteine knot superfamily 1, BMP antagonist 3
• DAN domain family member 5
• DAN domain family, member 5
• DAND5
• Dante
• DTE
• FLJ38607
• GREM3
• GREM3cerberus 2
• gremlin-3
• SP1

Background

DAND5, also known as DAN domain family member 5, is a 20 kDa 189 amino acid protein that forms homodimers and heterodimers as a member of the BMP antagonist family. Current research involving the protein includes connections with syrigoma, myopia, norrie disease, astigmatism, and carcinoma. The protein also plays important roles in tissue growth and differentiation pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DAND5