COCO/DAND5 Antibody (322206) [PerCP]

• Reactivity: Hu
• Applications: WB
• Clone: 322206
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP

COCO/DAND5 Antibody (322206) [PerCP] Summary

• Immunogen: E. coli-derived recombinant human COCO
  Arg23-Ala189
  Accession # Q8N907
• Specificity: Detects human COCO in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) COCO, rmGremlin, rmPRDC, recombinant human (rh) DAN, rhCerberus, or recombinant chicken Caronte is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: DAND5
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for COCO/DAND5 Antibody (322206) [PerCP]

• CER2CRL2
• Cerberus 2
• Cerberus like-2
• cerberus-like 2
• Cerberus-like protein 2
• CERL2
• cerl-2
• CKTSF1B3
• CKTSF1B3MGC126849
• COCO
• Cysteine knot superfamily 1, BMP antagonist 3
• DAN domain family member 5
• DAN domain family, member 5
• DAND5
• Dante
• DTE
• FLJ38607
• GREM3
• GREM3cerberus 2
• gremlin-3
• SP1

Background

DAND5, also known as DAN domain family member 5, is a 20 kDa 189 amino acid protein that forms homodimers and heterodimers as a member of the BMP antagonist family. Current research involving the protein includes connections with syrigoma, myopia, norrie disease, astigmatism, and carcinoma. The protein also plays important roles in tissue growth and differentiation pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DAND5