Coagulation Factor XI Antibody (007) - Azide and BSA Free

• Reactivity: Hu
• Applications: ELISA
• Clone: 007
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Coagulation Factor XI Antibody (007) - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human Coagulation Factor XI (Accession#: NP_000119.1; Met1-Val625).
• Specificity: No cross-reactivity in ELISA with:
  
  Human FX
  Human uPA
  Human KLK1
  Human KLK11
  Human HGFA
  Human KLK3
  Human KLK4
  Human KLK8
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: F11
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:5000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for Coagulation Factor XI Antibody (007) - Azide and BSA Free

• Coagulation Factor XI
• EC 3.4.21
• EC 3.4.21.27
• FXIPlasma thromboplastin antecedent
• MGC141891
• PTA

Background

Factor XI encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: F11