Coagulation Factor XI Products

Antibodies
Coagulation Factor XI Antibod ...
Coagulation Factor XI Antibody
AF2460
Species: Hu
Applications: WB, IP, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Coagulation Factor XI Antibod ...
Coagulation Factor XI Antibody (31...
MAB24601
Species: Hu
Applications: WB, IP, Neut
Host: Mouse Monoclonal
Coagulation Factor XI Antibod ...
Coagulation Factor XI Antibody (31...
MAB2460
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
Antibody Pairs
Coagulation Factor XI Antibod ...
Coagulation Factor XI Antibody Pair
H00002160-PW1
Species: Hu
Applications: WB, IP
Coagulation Factor XI Antibod ...
Coagulation Factor XI Antibody Pair
H00002160-PW2
Species: Hu
Applications: WB, IP
ELISA Kits
Coagulation Factor XI ELISA K ...
Coagulation Factor XI ELISA Kit [B...
KA1400
Species: Hu
Lysates
Coagulation Factor XI Overexp ...
Coagulation Factor XI Overexpressi...
H00002160-T01
Species: Hu
Applications: WB
Coagulation Factor XI Overexp ...
Coagulation Factor XI Overexpressi...
NBL1-10403
Applications: WB
Proteins
Coagulation Factor XI Partial ...
Coagulation Factor XI Partial Reco...
H00002160-Q01
Species: Hu
Applications: WB, ELISA, PA
Coagulation Factor XI Recombi ...
Coagulation Factor XI Recombinant ...
H00002160-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Coagulation Factor XI RNAi
Coagulation Factor XI RNAi
H00002160-R01
Species: Hu

Description

Factor XI encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 2160
Alternate Names
  • EC 3.4.21
  • PTA
  • EC 3.4.21.27
  • FXIPlasma thromboplastin antecedent
  • MGC141891
  • coagulation factor XI

Research Areas for Coagulation Factor XI

Find related products by research area and learn more about each of the different research areas below.

Prostate Cancer

PTMs for Coagulation Factor XI

Learn more about PTMs related to Coagulation Factor XI.

Phosphorylation
Glycosylation
Cleavage
Deglycosylation
Carboxylation
Hydroxylation
Dephosphorylation
Acylation
Gpi Anchoring

Bioinformatics Tool for Coagulation Factor XI

Discover related pathways, diseases and genes to Coagulation Factor XI. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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