CNAP1 Antibody

Western Blot: CNAP1 Antibody [NB100-1570] - Detection of Human CAP-D2 on HeLa whole cell lysate using NB100-1570.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

CNAP1 Antibody Summary

• Description: Novus Biologicals Rabbit CNAP1 Antibody (NB100-1570) is a polyclonal antibody validated for use in WB and IP. Anti-CNAP1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1350 and the C-terminus (residue 1401) of human Chromosome Associated Protein D2 (NP_055680.2)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NCAPD2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1-4 ug/mg of lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CNAP1 Antibody

• CAPD2
• CAP-D2
• Chromosome condensation-related SMC-associated protein 1
• Chromosome-associated protein D2
• CNAP1XCAP-D2 homolog
• hCAP-D2condensin complex subunit 1
• KIAA0159chromosome condensation related SMC associated protein 1
• Non-SMC condensin I complex subunit D2
• non-SMC condensin I complex, subunit D2

Background

CAP-D2 is a subunit of the heteropentameric condensin I complex. Condensin participates in the condensation of chromosomes during cell division by facilitating positive DNA supercoiling and knotting by topoisomerase I and II and proper segregation of sister chromatids. In the condensin complex CAP-D2 may be important for targeting condensin to mitotic chromosomes as well as metaphase alignment of sister chromatids. Alternate designations for CAP-D2 include condensin complex subunit 1, non-SMC condensin complex subunit D2, chromosome condensation-related SMC-associated protein 1, chromosome-associated protein D2, hCAP-D2, XCAP-D2 homolog, NCAPD2, CAPD2, CNAP1, and KIAA0159.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CNAP1 Antibody (NB100-1570)(1)

Publication using NB100-1570

• Manning AL, Longworth MS, Dyson NJ et al. Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev 2010-07-01 [PMID: 20551165]

Bioinformatics

• Gene Symbol: NCAPD2
• Entrez:
  • 9918(Human)
• Uniprot:
  • Q15021(Human)