CNAP1 Antibody (24GB75)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, Mycoplasma
• Clone: 24GB75
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

CNAP1 Antibody (24GB75) Summary

• Immunogen: A synthesized peptide derived from human CNAP1 (Uniprot: Q15021)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: NCAPD2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CNAP1 Antibody (24GB75)

• CAPD2
• CAP-D2
• Chromosome condensation-related SMC-associated protein 1
• Chromosome-associated protein D2
• CNAP1XCAP-D2 homolog
• hCAP-D2condensin complex subunit 1
• KIAA0159chromosome condensation related SMC associated protein 1
• Non-SMC condensin I complex subunit D2
• non-SMC condensin I complex, subunit D2

Background

CNAP1/hCAP-D2 is a regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. It may target the condensin complex to DNA via its C-terminal domain (referenced from Swissprot).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NCAPD2