Recombinant Human CMP kinase Protein

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SDS-Page: Recombinant Human CMP kinase Protein [NBP1-51052] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human CMP kinase Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-228 of Human CMP kinase

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CMPK1
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT, 100mM NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human CMP kinase Protein

  • CMKEC 2.7.4.14
  • CMPKUMKUMP-CMP kinase
  • cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
  • Cytidine monophosphate kinase
  • Cytidylate kinaseUMP/CMP kinase
  • Deoxycytidylate kinase
  • EC 2.7.4
  • UMP/CMPK
  • UMP-CMPK
  • UMPKUCK
  • Uridine monophosphate kinase
  • Uridine monophosphate/cytidine monophosphate kinase

Background

CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. Recombinant human CMPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CMPK1