CLK2 Antibody - BSA Free

Western Blot: CLK2 Antibody [NBP1-32647] - (30 ug whole cell lysate) A:HeLa S3 7.5% SDS PAGE diluted at 1:1000

• Reactivity: Hu, Mu, Rt, Bv, Ch
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CLK2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CLK2 Antibody - BSA Free (NBP1-32647) is a polyclonal antibody validated for use in WB. Anti-CLK2 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CLK2. The exact sequence is proprietary.
• Localization: Nucleus
• Predicted Species: Mouse (98%), Rat (98%), Chicken (94%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLK2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 60 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (88%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for CLK2 Antibody - BSA Free

• CDC-like kinase 2
• CDC-like kinase 2CLK kinase
• CLK2
• dual specificity protein kinase CLK2
• EC 2.7.12.1
• hCLK2
• MGC61500

Background

This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for CLK2 Antibody (NBP1-32647)(1)

Publication using NBP1-32647

• Liu S, Wu R, Chen L et al. CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation Cell reports 2023-10-31 [PMID: 37777964]

Bioinformatics

• Gene Symbol: CLK2
• Entrez:
  • 1196(Human)
• Uniprot:
  • P49760(Human)