CLEC-2/CLEC-1B Antibody (1C10) - Azide and BSA Free

Sandwich ELISA: CLEC-2/CLEC-1B Antibody (1C10) [H00051266-M02] - Detection limit for recombinant GST tagged CLEC1B is 1 ng/ml as a capture antibody.

Immunoprecipitation: CLEC-2/CLEC-1B Antibody (1C10) [H00051266-M02] - Analysis of CLEC1B transfected lysate using anti-CLEC1B monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with CLEC1B MaxPab rabbit polyclonal antibody.

• Reactivity: Hu
• Applications: WB, ELISA, IP
• Clone: 1C10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CLEC-2/CLEC-1B Antibody (1C10) - Azide and BSA Free Summary

• Immunogen: CLEC1B (NP_057593, 128 a.a. ~ 229 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QYCTDMNATLLKIDNRNIVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISENMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP
• Specificity: CLEC1B - C-type lectin domain family 1, member B (1C10)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CLEC1B
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CLEC-2/CLEC-1B Antibody (1C10) - Azide and BSA Free

• 1810061I13Rik
• CLEC1B
• CLEC2
• CLEC-2
• CLEC2B
• CLEC2PRO1384
• C-type lectin domain family 1 member B
• C-type lectin domain family 1, member B
• C-type lectin-like receptor 2
• C-type lectin-like receptor-2
• QDED721

Background

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CLEC-2/CLEC-1B Antibody (H00051266-M02)(1)

Publication using H00051266-M02

• Manne BK, Badolia R, Dangelmaier CA, Kunapuli SP. C-type lectin like-receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets. Biochem Pharmacol. 2014-11-20 [PMID: 25462818]

Bioinformatics

• Gene Symbol: CLEC1B
• Entrez:
  • 51266(Human)
• Uniprot:
  • NP_057593()