CLCN5 Antibody

Western Blot: CLCN5 Antibody [NBP1-32302] - Sample(30 ug of whole cell lysate) A:A431 7. 5% SDS PAGE, antibody diluted at 1:500.

Product Discontinued

CLCN5 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human CLCN5. The exact sequence is proprietary.
• Localization: Golgi apparatus membrane, Endosome membrane, Cell membrane
• Predicted Species: Mouse (96%), Rat (97%), Porcine (98%), Guinea Pig (97%), Rabbit (98%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLCN5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 83 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (86%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for CLCN5 Antibody

• chloride channel 5
• Chloride channel protein 5
• Chloride transporter ClC-5
• CLC5
• clC-5
• CLCK2NPHL2
• DENTSNPHL1
• H(+)/Cl(-) exchange transporter 5
• hCIC-K2
• hClC-K2
• nephrolithiasis 1 (X-linked)
• nephrolithiasis 2, X-linked
• XLRH
• XRN

Background

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CLCN5