Claudin-4 Antibody (382321) [Unconjugated]

Images

 
PC‑3 human prostate cancer cell line was stained with Mouse Anti-Human Claudin‑4 Monoclonal Antibody (Catalog # MAB4219, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram) followed ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
382321
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Claudin-4 Antibody (382321) [Unconjugated] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Claudin-4
Met1-Val209
Accession # NP_001296
Specificity
Detects human Claudin‑4. Stains human Claudin-4 transfectants but not irrelevant transfectants. Recognizes an epitope in the first extracellular loop (aa Met29-Arg81).
Details of Functionality
ActivityAssaywCitation not found None
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CLDN4
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25 ug/10^6 cells
  • CyTOF-ready
Publications
Read Publication using
MAB4219 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Claudin-4 Antibody (382321) [Unconjugated]

  • claudin 4
  • Claudin4
  • Claudin-4
  • CLDN4
  • Clostridium perfringens enterotoxin receptor 1
  • Clostridium perfringens enterotoxin receptor
  • CPE-R
  • CPE-RCPETR
  • CPE-receptor
  • CPETR1
  • hCPE-R
  • WBSCR8
  • WBSCR8CPERCPETR1claudin-4
  • Williams-Beuren syndrome chromosomal region 8 protein

Background

Claudin-4 is a multipass membrane protein in the claudin family of tight junction proteins. Claudin-4 is a 209 amino acid molecule with four transmembrane segments. It is preferentially expressed in intestinal mucosa epithelium and is involved in epithelial tissue development. It is also up‑regulated in several carcinomas. Phosphorylation of Claudin-4 regulates paracellular epithelial permeability. Human Claudin-4 shares 83% aa sequence identity with mouse and rat Claudin-4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Claudin-4 Antibody (MAB4219)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: CyTof.


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CyTof
(1)
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FAQs for Claudin-4 Antibody (MAB4219) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB4219U
Alexa Fluor 405 FAB4219V
Alexa Fluor 488 FAB4219G
Alexa Fluor 594 FAB4219T
Alexa Fluor 647 FAB4219R
Alexa Fluor 700 FAB4219N
Alexa Fluor 750 FAB4219S
Allophycocyanin FAB4219A
Fluorescein FAB4219F
Phycoerythrin FAB4219P

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Bioinformatics

Gene Symbol CLDN4
Uniprot