Claudin-4 Antibody (382316) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 382316
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

Claudin-4 Antibody (382316) [Alexa Fluor® 594] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human Claudin-4
  Met1-Val209
  Accession # NP_001296
• Specificity: Detects human Claudin-4 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Claudin-4 Antibody (382316) [Alexa Fluor® 594]

• claudin 4
• Claudin4
• Claudin-4
• CLDN4
• Clostridium perfringens enterotoxin receptor 1
• Clostridium perfringens enterotoxin receptor
• CPE-R
• CPE-RCPETR
• CPE-receptor
• CPETR1
• hCPE-R
• WBSCR8
• WBSCR8CPERCPETR1claudin-4
• Williams-Beuren syndrome chromosomal region 8 protein

Background

Claudin-4 is a multipass membrane protein in the claudin family of tight junction proteins. Claudin-4 is a 209 amino acid molecule with four transmembrane segments. It is preferentially expressed in intestinal mucosa epithelium and is involved in epithelial tissue development. It is also up‑regulated in several carcinomas. Phosphorylation of Claudin-4 regulates paracellular epithelial permeability. Human Claudin-4 shares 83% aa sequence identity with mouse and rat Claudin-4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.