Claudin-1 Antibody Pair

Product Discontinued

Claudin-1 Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00009076-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CLDN1.
  
  
• Capture antibody: rabbit MaxPab affinity purified polyclonal anti-CLDN1 (100 ug)
• Detection antibody: mouse monoclonal anti-CLDN1 IgG2a Kappa (20 ug)
• Standard Curve Range: 3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: CLDN1

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Claudin-1 Antibody Pair

• claudin 1
• Claudin1
• Claudin-1
• CLD1
• CLDN1
• ILVASCSenescence-associated epithelial membrane protein
• SEMP1
• SEMP1senescence-associated epithelial membrane protein 1

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CLDN1