Claudin-1 Products

Description

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Bioinformatics

Entrez	12737 Mouse 414922 Bovine 65129 Rat 9076 Human
Uniprot	AAH12471 Human AAH12471.1 Human CAG33419 Human NM_021101 Human NP_066924 Human NP_066924.1 Human O95832 Human
Product By Gene ID	9076
Alternate Names	claudin 1 claudin-1 CLD1 ILVASCSenescence-associated epithelial membrane protein SEMP1senescence-associated epithelial membrane protein 1

Research Areas for Claudin-1

Find related products by research area and learn more about each of the different research areas below.

Extracellular Matrix

Related Claudin-1 Blog Posts

Check out the latest blog posts on Claudin-1.

Nickel induces migratory and invasive phenotype in human epithelial cells by epigenetically activating ZEB1 By Jamshed Arslan Pharm.D. Nickel (Ni) is a naturally abundant metallic element. It is a major component of stainless steel, coins, and many other items of daily use. Disturbingly, Ni exposure is associated with can...    Read more.

Read more Claudin-1 related blogs.