Immunohistochemistry-Paraffin: CKMT2 Antibody [NBP2-13841] - Staining of human lymph node shows low expression as expected.
Immunohistochemistry-Paraffin: CKMT2 Antibody [NBP2-13841] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.
Orthogonal Strategies: Immunohistochemistry-Paraffin: CKMT2 Antibody [NBP2-13841] - Staining in human heart muscle and lymph node tissues using anti-CKMT2 antibody. Corresponding CKMT2 RNA-seq data are presented ...read more
Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%)
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 40% Glycerol
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for CKMT2 Antibody
Basic-type mitochondrial creatine kinase
creatine kinase S-type, mitochondrial
creatine kinase, mitochondrial 2 (sarcomeric)
Sarcomeric mitochondrial creatine kinase
CKMT2 belongs to the creatine kinase isoenzyme family, and is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It exists as two isoenzymes, sarcomeric CKMT2 and ubiquitous CKMT2, which are encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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