Chondromodulin-1/LECT1 Antibody (394002) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: 394002
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Chondromodulin-1/LECT1 Antibody (394002) [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Chondromodulin‑1 mature chain
  Glu215-Val333
  Accession # NP_001011705.1
• Specificity: Detects human Chondromodulin‑1 in direct ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Chondromodulin-1/LECT1 Antibody (394002) [Alexa Fluor® 488]

• BRICD3
• BRICHOS domain containing 3
• ChM-1
• CHM1chondromodulin I
• CHMI
• CHM-I
• chondromodulin
• Chondromodulin1
• Chondromodulin-1
• chondromodulin-I
• LECT1
• leukocyte cell derived chemotaxin 1
• Leukocyte cell-derived chemotaxin 1
• multiple myeloma tumor suppressor 1
• MYETS1

Background

Chondromodulin-1 (ChM-1), also known as Lect1, is a type II transmembrane protein that is cleaved intracellularly resulting in the secretion of a 25 kDa molecule. ChM-1 is expressed in avascular cartilage, cardiac valves, and the eye. The antiangiogenic properties of ChM-1 can block tumor progression and the pathological vascularization of cardiac valves. Human ChM-1 shares 89%‑92% aa sequence identity with bovine, mouse, rabbit, and rat ChM-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • NP_001011705.1()