CENPJ Antibody Pair

Product Discontinued

CENPJ Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: mouse monoclonal anti-CENPJ (300 ug)
• Antibody pair for WB: rabbit polyclonal anti-CENPJ (50 ul)
• Clonality: Polyclonal
• Gene: CENPJ
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CENPJ Antibody Pair

• BM032
• CENP-J
• centromere protein J
• Centrosomal P4.1-associated protein
• CPAPMCPH6
• LAG-3-associated protein
• LAPSCKL4
• LIP1microcephaly, primary autosomal recessive 6
• LYST-interacting protein 1
• LYST-interacting protein LIP1
• LYST-interacting protein LIP7
• MGC131581
• MGC131582
• MGC142222
• MGC142224
• Sas-4
• SASS4

Background

CENPJ encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CENPJ