Recombinant Human CDKN3 Protein

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SDS-Page: Recombinant Human CDKN3 Protein [NBP1-50909] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human CDKN3 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-212 of Human CDKN3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MKPPSSIQTS EFDSSDEEPI EDEQTPIHIS WLSLSRVNCS QFLGLCALPG CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG IITHHHPIAD GGTPDIASCC EIMEELTTCL KNYRKTLIHC YGGLGRSCLV AACLLLYLSD TISPEQAIDS LRDLRGSGAI QTIKQYNYLH EFRDKLAAHL SSRDSQSRSV SR

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CDKN3
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
25.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.1M NaCl
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human CDKN3 Protein

  • CDI1KAP1
  • CDK2-associated dual specificity phosphatase
  • CDK2-associated dual-specificity phosphatase
  • Cdk-associated protein phosphatase
  • CIP2
  • cyclin-dependent kinase inhibitor 3
  • cyclin-dependent kinase interacting protein 2
  • Cyclin-dependent kinase interactor 1
  • Cyclin-dependent kinase-interacting protein 2
  • EC 3.1.3.16
  • EC 3.1.3.48
  • FLJ25787
  • KAPMGC70625
  • Kinase-associated phosphatase

Background

Cyclin-dependent kinase inhibitor 3, also known CDKN3, belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. Also CDKN3 is important in cell cycle regulation. Recombinant human CDKN3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CDKN3