Cdk7 Antibody

Western Blot: Cdk7 Antibody [NBP2-15847] - A. 30 ug C8D30 whole cell lysate/extract. B. 30 ug NIH-3T3 whole cell lysate/extract. C. 30 ug BCL-1 whole cell lysate/extract. D. 30 ug Raw264.7 whole cell lysate/extract E. 30 ug C2C12 whole cell lysate/extract.

Immunohistochemistry-Paraffin: Cdk7 Antibody [NBP2-15847] - Analysis of paraffin-embedded OVCA, using antibody at 1:250 dilution.

Western Blot: Cdk7 Antibody [NBP2-15847] - A. 30 ug HeLa whole cell lysate/extract. B. 30 ug HepG2 whole cell lysate/extract.

Product Discontinued

Cdk7 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human CDK7. The exact sequence is proprietary.
• Localization: Nucleus
• Predicted Species: Porcine (97%), Bovine (96%), Rhesus Macaque (99%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDK7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 39 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Zebrafish (84%), Xenopus laevis (86%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for Cdk7 Antibody

• CAK1Xenopus laevis, cdk-activating kinase)
• Cdk7
• CDK-activating kinase
• CDKN7
• Cell division protein kinase 7
• cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
• cyclin-dependent kinase 7
• EC 2.7.11
• EC 2.7.11.22
• EC 2.7.11.23
• EC 2.7.11.24
• MO15
• p39 Mo15
• serine/threonine kinase stk1,39 kDa protein kinase
• serine/threonine protein kinase 1
• serine/threonine protein kinase MO15
• STK1
• TFIIH basal transcription factor complex kinase subunit

Background

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CDK7
• Uniprot:
  • P50613(Human)