CDC45L Antibody

Western Blot: CDC45L Antibody [H00008318-B01P] - Analysis of CDC45L expression in transfected 293T cell line by CDC45L polyclonal antibody. Lane 1: CDC45L transfected lysate(62.26 KDa). Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: CDC45L Antibody [H00008318-B01P] - Analysis of purified antibody to CDC45L on HeLa cell. (antibody concentration 10 ug/ml)

Immunohistochemistry-Paraffin: CDC45L Antibody [H00008318-B01P] - Analysis of purified antibody to CDC45L on formalin-fixed paraffin-embedded human placenta. (antibody concentration 3 ug/ml)

Product Discontinued

CDC45L Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CDC45L (NP_003495.1, 1 a.a. - 566 a.a.) full-length human protein. MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELETAFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIKQDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEARRRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVTDVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARFKLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQTFSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAKKQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCSTKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHNHFDLSVIELKAEDRSKFLDALISLLS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CDC45
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: This antibody is useful for WB, Functional, IF and IHC-P.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CDC45L Antibody

• CDC45 cell division cycle 45-like (S. cerevisiae)
• cell division cycle 45 homolog (S. cerevisiae)
• cell division cycle 45-like 2
• human CDC45
• S.cerevisiae, homolog)-like

Background

CDC45L is encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC45
• Uniprot:
  • NP_003495.1(Human)