Cdc27 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

Cdc27 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 19 amino acids near the carboxy terminus of human APC3.

  Source: Synthetic

  (Accession #: NP_001247)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: CDC27
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-77377.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for Cdc27 Antibody Blocking Peptide

• ANAPC3CDC27 homolog
• anaphase promoting complex subunit 3
• Anaphase-promoting complex subunit 3
• anaphase-promoting complex, protein 3
• APC 3
• APC3cell division cycle 27
• CDC27Hs
• cell division cycle 27 homolog (S. cerevisiae)
• cell division cycle protein 27 homolog
• D0S1430E
• D17S978E
• HNUC
• H-NUC
• nuc2 homolog
• NUC2

Background

Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CDC27