Cdc27 Products

Description

Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.

Bioinformatics

Entrez	217232 Mouse 360643 Rat 996 Human
Uniprot	NM_001256 Human NP_001107563 Human NP_001247 Human P30260 Human
Product By Gene ID	996
Alternate Names	ANAPC3CDC27 homolog anaphase promoting complex subunit 3 Anaphase-promoting complex subunit 3 anaphase-promoting complex, protein 3 APC 3 APC3cell division cycle 27 CDC27Hs cell division cycle 27 homolog (S. cerevisiae) cell division cycle protein 27 homolog D0S1430E D17S978E HNUC H-NUC nuc2 homolog NUC2

Research Areas for Cdc27

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Phospho-Specific