Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free

• Reactivity: Xp
• Applications: WB, ELISA
• Clone: BT2.1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free Summary

• Description: Novus Biologicals Mouse Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free (NBP2-50246) is a monoclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: GPKMQGpTPSRAG. pT represents phosphorylated Thr79.
• Modification: p Thr79
• Clonality: Monoclonal
• Host: Mouse
• Gene: CDC20
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Western Blot 1:100 - 1:2000
• Application Notes: Positive control(s): Xenopus egg extract.
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free

• CDC20 cell division cycle 20 homolog (S. cerevisiae)
• CDC20 cell division cycle 20 homolog
• Cdc20
• cell division cycle 20 homolog (S. cerevisiae)
• cell division cycle protein 20 homolog
• MGC102824
• p55CDC
• p55CDCS. cerevisiae, homolog)

Background

CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC20