CD84/SLAMF5 Antibody (CD84.1.21) [DyLight 755]

• Reactivity: Hu
• Applications: Flow, IP
• Clone: CD84.1.21
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 755

CD84/SLAMF5 Antibody (CD84.1.21) [DyLight 755] Summary

• Description: This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
• Immunogen: Mouse pre-B cell line 300.19 transfected with CD84 cDNA
• Localization: Type I membrane protein
• Specificity: NB100-65929 recognizes the human CD84 cell surface antigen, a highly glycosylated cell surface antigen of 64-82kD. CD84 is predominantly expressed by B lymphocytes, monocytes and macrophages, although lower levels of expression have also been reported on T cells, granulocytes and platelets.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD84
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunoprecipitation

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD84/SLAMF5 Antibody (CD84.1.21) [DyLight 755]

• CD84 antigen (leukocyte antigen)
• CD84 antigen
• CD84 molecule
• CD84
• Cell surface antigen MAX.3
• DKFZp781E2378
• hCD84
• hly9-beta
• leucocyte differentiation antigen CD84
• leukocyte antigen CD84
• Leukocyte differentiation antigen CD84
• Ly-9B
• mCD84
• Signaling lymphocytic activation molecule 5
• SLAM family member 5
• SLAMF5
• SLAMF5LY9B

Background

CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. CD84 is expressed on mature B cells and B cell lines but not on plasma cell lines. Immunohistochemical studies demonstrate that it strongly stains tissue macrophages. It is also expressed on platelets and at low levels on blood T cells. Cellular expression does not significantly increase after activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD84
• Entrez:
  • 8832(Human)
• Uniprot:
  • Q9UIB8(Human)