CD72 Antibody (BU40) [PerCP]

• Reactivity: Hu, RM
• Applications: WB, Flow, IHC, IP, CyTOF-ready
• Clone: BU40
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP

CD72 Antibody (BU40) [PerCP] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Additional Information: Clone BU40 was used by HLDA to establish CD designation.
• Immunogen: HF B1 plasmacytoid cell line. Considered to be late B like.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD72
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-64350. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

Use in Rhesus Macaque reported in scientific literature (PMID:32023469).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD72 Antibody (BU40) [PerCP]

• CD72 antigenB-cell differentiation antigen CD72
• CD72 molecule
• CD72
• CD72b
• Ly-19.2
• Ly-32.2
• Lyb-2
• LYB2lyb-2

Background

CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface molecules such as the asialoglycoprotein receptors, CD23 and the Kupffer cell receptor. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD72 Antibody (NB100-64350PCP)(1)

Publication using NB100-64350PCP

• Han Q, Bradley T et al Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization Cell Rep 2020-02-06 [PMID: 32023469] (FLOW, FLOW, Rhesus Macaque)
  
  Details:
  Citation using the PerCP version of this antibody.

Bioinformatics

• Gene Symbol: CD72