CD38 Antibody (90) [DyLight 550] Summary
Mouse bone marrow pre-B cells
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C in the dark.
DyLight 550 (A=562, E=576)
50mM Sodium Borate
0.05% Sodium Azide
Protein A or G purified
- Flow Cytometry 1:10-1:1000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Frozen 1:10-1:500
Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections, and induction of B cell proliferation.
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for CD38 Antibody (90) [DyLight 550]
- ADP-ribosyl cyclase 1
- ADP-ribosyl Cyclase
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- cADPr hydrolase 1
- CD38 antigen (p45)
- CD38 antigen
- CD38 molecule
- Cyclic ADP-ribose hydrolase 1
- Cyclic ADP-ribose Hydrolase
- EC 188.8.131.52
- NAD(+) nucleosidase
CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, subset of T cells, brain, muscle, and kidney. In the mouse, CD38 expression is downregulated on mouse germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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FAQs for CD38 Antibody (NB100-77405R). (Showing 1 - 1 of 1 FAQ).
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Other Available Formats
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Blogs on CD38.
Transferrin and the blood brain barrier
Transferrin, an iron binding protein that facilitates iron uptake in cells, is an integral part of a mechanism that may introduce antibody therapies to the central nervous system. Currently, the brain’s ability to take in antibody therapies i... Read full blog post.
CD38 is a 42 kD type II transmembrane glycoprotein that uses nicotinamide adenine dinucleotide (NAD) as a substrate to form cyclic adenosine diphosphate ribose (cADPR). This novel multifunctional ectoenzyme has both cyclase and hydrolase enzymatic act... Read full blog post.