CD37 Antibody (IPO-24)

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SDS-Page: CD37 Antibody (IPO-24) [NBP2-44750]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, PAGE, ICC/IF
Clone
IPO-24
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

CD37 Antibody (IPO-24) Summary

Immunogen
Spleen cells of a patient with hairy cell leukemia
Localization
Cell Surface
Marker
Peripheral Mature B-Cell Marker
Specificity
Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin's lymphoma (B-NHL).
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD37
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml
  • SDS-Page
  • Immunofluorescence 0.5 - 1.0 ug/ml
Application Notes
Hu-chromosome location: 19q13.3
Molecular weight of antigen: 33-55kDa Functional Studies Order Ab without Azide.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10mM PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for CD37 Antibody (IPO-24)

  • CD37 antigentetraspanin-26
  • CD37 molecule
  • CD37
  • cell differentiation antigen 37
  • GP52-40
  • leukocyte antigen CD37
  • MGC120234
  • Tetraspanin-26
  • TSPAN26
  • tspan-26
  • TSPAN26leukocyte surface antigen CD37

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Blogs on CD37.

CD81/TAPA1: I'm on Tapa the Cell
Target of the antiproliferative 1 (TAPA1), also known as CD81, is found in the plasma membrane in lymphocytes and plays an important role in the regulation of lymphoma cell growth. This transmembrane 4 superfamily (TM4SF) protein is primarily found on...  Read full blog post.

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Bioinformatics

Gene Symbol CD37
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