Reactivity | HuSpecies Glossary |
Applications | IHC, IHC-P |
Clone | SPM609 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Biotin |
Immunogen | Recombinant human TNFRSF8 protein |
Localization | Cell surface |
Marker | Hodgkin & Reed-Sternberg Cell Marker |
Specificity | Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45). |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | TNFRSF8 |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
|
Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Readout System |
Storage | Store at 4C in the dark. |
Buffer | PBS |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | NBP2-47907AF350 | |
Alexa Fluor 405 | NBP2-47907AF405 | |
Alexa Fluor 488 | NBP2-47907AF488 | |
Alexa Fluor 532 | NBP2-47907AF532 | |
Alexa Fluor 594 | NBP2-47907AF594 | |
Alexa Fluor 647 | NBP2-47907AF647 | |
Alexa Fluor 700 | NBP2-47907AF700 | |
Alexa Fluor 750 | NBP2-47907AF750 | |
Allophycocyanin | NBP2-47907APC | |
Biotin | NBP2-47907B | |
DyLight 350 | NBP2-47907UV | |
DyLight 405 | NBP2-47907V | |
DyLight 488 | NBP2-47907G | |
DyLight 550 | NBP2-47907R | |
DyLight 594 | NBP2-47907DL594 | |
DyLight 650 | NBP2-47907C | |
DyLight 680 | NBP2-47907FR | |
DyLight 755 | NBP2-47907IR | |
FITC | NBP2-47907F | |
HRP | NBP2-47907H | |
Janelia Fluor 549 | NBP2-47907JF549 | |
Janelia Fluor 646 | NBP2-47907JF646 | |
PE | NBP2-47907PE | |
PerCP | NBP2-47907PCP |
Diseases for CD30/TNFRSF8 Antibody (NBP2-47907B)Discover more about diseases related to CD30/TNFRSF8 Antibody (NBP2-47907B).
| Pathways for CD30/TNFRSF8 Antibody (NBP2-47907B)View related products by pathway.
|
Research Areas for CD30/TNFRSF8 Antibody (NBP2-47907B)Find related products by research area.
|
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
Gene Symbol | TNFRSF8 |