CD27 Ligand/TNFSF7/CD70 Antibody (Ki-24) - BSA Free

Flow Cytometry: CD27 Ligand/TNFSF7/CD70 Antibody (Ki-24) [NBP3-09122] - Separation of HUT-78 cells (red-filled) from SP2 cells (black-dashed) in flow cytometry analysis (surface staining) of cell lines stained using anti-human CD70 (Ki-24) purified antibody (concentration in sample 1 ug/ml) GAM APC.

Flow Cytometry: CD27 Ligand/TNFSF7/CD70 Antibody (Ki-24) [NBP3-09122] - Surface staining pattern of HUT-78 cells stained using anti-human CD70 (Ki-24) purified antibody (concentration in sample 1 ug/ml) GAM APC.

• Reactivity: Hu
• Applications: Flow
• Clone: Ki-24
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CD27 Ligand/TNFSF7/CD70 Antibody (Ki-24) - BSA Free Summary

• Additional Information: Clone Ki-24 was used by HLDA to establish CD designation.
• Immunogen: Human L428 Cell Line
• Specificity: The mouse monoclonal antibody Ki-24 recognizes an extracellular epitope of CD70, an approximately 50 kDa type II transmembrane glycoprotein expressed on activated lymphocytes and some B cell leukemias.
• Isotype: IgG3 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD70
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-5 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for CD27 Ligand/TNFSF7/CD70 Antibody (Ki-24) - BSA Free

• CD27 Ligand
• CD27-L
• CD27LCD27 ligand
• CD27LG
• CD70 molecule
• CD70
• Ki-24 antigen
• surface antigen CD70
• TNFSF7
• TNFSF7CD70 antigen
• tumor necrosis factor (ligand) superfamily, member 7
• Tumor necrosis factor ligand superfamily member 7

Background

CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD70